Interior Design is seeking its own way as an independent field from architecture, essentially since the creation of the university career. Even though they share several logic and analytic aspects, gradually the thought mechanisms begin to take off themselves in order to work different scale, space conception, precision and even sensitivity. This process of conceptual dissociation requires several strategies, like the strengthening of theoretical frame works. In that sense, this essay proposes, by means of the historical analysis, a search of theoretical sustenance in order to consolidate the emerging discipline of interior design in terms of its own specificity, autonomy and logic. For that reason, the essay focuses in identifying those specific components that describe the evolution of the interior design in history. For this first edition, cult spaces were selected as the subject. Drivers like the inner-outer relation ; the functionality and circulations; the morphology, the dimension and the scale; the materials, the coatings, ornamentation, the equipment and the furniture; the light and the color; the sensorial perception; the symbolism and the iconography, were chosen to be applied to a work by different relevant artistic movements. This glance on the plastic and functional configuration of the internal space will be receiving gradually, a logic, a methodology, a corpus of own ideas and a language.